RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-214
RNA ID
RNA Type
miRNA
Alteration Pattern
dysregulation
Species
mus musculus
Detection Methods
RT-PCR; immunohistochemical; dual-lucimmunofluorescenceerase reporter assay etc.
Target
CCN2 3'-UTR
Pathway
NA
PubMed ID
Title
Epigenetic regulation of connective tissue growth factor by MicroRNA-214 delivery in exosomes from mouse or human hepatic stellate cells
Year
2014
Function
Mkl1 deficiency ameliorated bdl-induced liver fibrosis in mice as assessed by histological stainings and expression levels of pro-fibrogenic genes.